文献类型：期刊文献

英文题名：Veronica anagallis-aquatica L. iridoid glycosides alleviate heart failure via metabolites homoveratrumic acid and 2-hydroxy-3,4-dimethoxybenzoic acid mediated by the gut microbiota

作者：Wang, Manjiong[1];Guo, Xiaobo[1];Liu, Hanfang[1];Li, Xiao[1];Yao, Yue[1];Fu, Qing[1];Jin, Yu[1];Ni, Shuaishuai[2];Li, Xiaokang[1];Xiao, Chaojiang[3,4];Jiang, Bei[3,4];Xia, Conglong[3,4];Li, Jian[1,5,6];Xu, Yixiang[1]

机构：[1]East China Univ Sci & Technol, Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Pharm,Shanghai Key Lab New Drug Design,State K, Shanghai 200237, Peoples R China;[2]Shanghai Univ Tradit Chinese Med, Longhua Hosp, Canc Inst, Shanghai 200032, Peoples R China;[3]Dali Univ, Inst Mat Med, Yunnan Key Lab Screening & Res Antipathogen Plant, Dali 671000, Peoples R China;[4]Dali Univ, Coll Pharm, Dali 671000, Peoples R China;[5]Shihezi Univ, Sch Pharm, Minist Educ, Key Lab Xinjiang Phytomed Resource & Utilizat, Shihezi 832003, Peoples R China;[6]Hainan Univ, Coll Pharm, Minist Educ, Key Lab Trop Biol Resources, Haikou 570228, Peoples R China

年份：2025

卷号：15

期号：6

起止页码：3338

外文期刊名：ACTA PHARMACEUTICA SINICA B

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001568411900025)】；

基金：This work was supported by the National Natural Science Foundation of China (22307038), National key R&D Program of China (2021YFA0804904), National Natural Science Foundation of China (32121005), National Natural Science Foundation of China (22107030), National Natural Science Foundation of China (22437002), National Natural Science Foundation of China (22037002), Innovation Program of Shanghai Municipal Education Commission (2021-01-07-00-02-E00104, China), Shanghai Frontier Science Center of Optogenetic Techniques for Cell Metabolism (2021 Sci & Tech 03-28, China), Innovative Research Team of High-level Local Universities in Shanghai (SHSMU-ZDCX20212702, China) and Chinese Special Fund for State Key Laboratory of Bioreactor Engineering (2060204).

语种：英文

外文关键词：Iridoid glycosides; Heart failure; Gut microbiota; Metabolite; Homoveratrumic acid; 2-Hydroxy-3,4-dimethoxybenzoic acid; Cardiac hypertrophy; HDAC2; HDAC2