文献类型：期刊文献

英文题名：Role of filled PLGA in improving enantioselectivity of Glu-GO/PLGA composite membranes

作者：Meng, Chenchen;Chen, Qibin[1];Tan, Huiling;Sheng, Yujie;Liu, Honglai[1]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2018

卷号：555

起止页码：398

外文期刊名：JOURNAL OF MEMBRANE SCIENCE

收录：;EI(收录号：20181404973519);WOS:【SCI-EXPANDED(收录号:WOS:000432587300041)】；

基金：This work is supported by the National Natural Science Foundation of China (No. 21576079, 21273074, 91334203), the 111 Project of Ministry of Education of China (No. B08021), and the Fundamental Research Funds for the Central Universities of China (WK1213003).

语种：英文

外文关键词：Enantioseparation; Composite membrane; Graphene oxide; Self-assembly; Chiral recognition

摘要：The primary aim of this investigation was to improve the chiral separation performance of graphene oxide (GO) based composite membranes via tuning the interlayer spacing between GO sheets using the association of poly(L-Glutamic acid sodium), PLGA, onto the surface of GO sheets. Results show that: i) compared with conventional chiral separation membranes, these membranes exhibit superior chiral resolution properties, which are 1-2 orders of magnitude higher in the flux and greater in the enantioselectivity; ii) compared with pristine L-Glutamic modified GO membranes, they also afford a significant improvement in enantioselectivity with a slight reduction in flux. In present work, it is demonstrated that in such composite membranes, the incorporated PLGA can not only serve as an additional chiral recognizing agent, facilitating the transport of D-isomer of the chiral probe, but also as a kind of filler, reducing the size of pores or channels between GO sheets. Especially, both roles can significantly contribute to enhancing the enantioselectivitiy of composite membranes. Our findings indicate that the combination of GO-based materials and polypeptides might offer unusual control in the selectivity and the flux of the corresponding composite membranes, achieved by regulating the interlayer spacing between GO sheets, and thus such composite membranes have a potential to simultaneously facilitate high-flux and high-selectivity and a promising application in a great number of enantio- and bio-separations.