文献类型：专利

英文题名：Preparation of niacin involves charging active sugar donor tetra-benzyl-1-O-alpha-D glucoslytri-chloroacetyl imine into solvent, carrying glycosylated reaction with hydroquinone and processing hydro-genolysis reaction to obtain product

作者：CHEN G;WANG Z;SHI X

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN100372861-C

公开日：2008-03-05

语种：英文

收录：DERWENT

摘要：NOVELTY - The invention relates to a process for preparing niacin which mainly comprises the following steps, at the presence of inert gas, charging active sugar donor 2,3,4,6-tetra-benzyl-1-O-alpha-D glucoslytri-chloroacetyl imine into solvent, at the presence of Lewis acid catalysis, carrying out glycosylated reaction with hydroquinone at -100 ~ 35 deg. C, thus obtaining intermediate compound 4-hydroxyphenyl-2',3',4',6'-tetra-O-benzyl-1'-O-alpha-D-glucopyranoside, finally carrying out hydro-genolysis reaction to obtain the destination product.