文献类型：期刊文献

英文题名：B10H12(MeCN)2 as a versatile reducing agent and its application in preparing carborane derivatives

作者：Hao, Guanxiang[1,2];Zhang, Yirong[1,2,3];Wang, Linyuan[1,2];Yuan, Changxian[1,2];Yin, Zhangxiang[1,2];Yang, Zekun[1,2];Wang, Ruizhi[1,2];Yu, Ting[1,2];Lou, Kaiyan[3];Wang, Sinan[1,2]

机构：[1]ShanghaiTech Univ, Sch Biomed Engn, Shanghai 201210, Peoples R China;[2]ShanghaiTech Univ, State Key Lab Adv Med Mat & Devices, Shanghai 201210, Peoples R China;[3]East China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2026

外文期刊名：ORGANIC CHEMISTRY FRONTIERS

收录：;EI(收录号：20261520487281);WOS:【SCI-EXPANDED(收录号:WOS:001736684500001)】；

基金：Financial support for this work was generously provided by ShanghaiTech University start-up funding.

语种：英文

外文关键词：Amides - Boron compounds - Reducing agents

摘要：B10H12(MeCN)2 is an important building block for the synthesis of o-carboranes. In this work, we found that B10H12(MeCN)2 can also serve as a reducing agent for aldehydes, nitro groups and amides. We demonstrated that B10H12(MeCN)2 can work as both a reducing agent and an o-carborane building block in one pot. A cascade reaction was designed and performed to synthesize 5,6-dihydrocarborano [5,4-c]quinoline compounds through a "one-pot, four-steps" pathway.