文献类型：期刊文献

英文题名：New strategy for the synthesis of 2-phenylbenzimidazole derivatives with sodium perborate (SPB) as oxidant

作者：Yuan, Jun[1];Zhao, Zhenjiang[2];Zhu, Weiping[1];Li, Honglin[2];Qian, Xuhong[1];Xu, Yufang[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China

年份：2013

卷号：69

期号：34

起止页码：7026

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000322098000012)，CCR-EXPANDED(收录号:WOS:000322098000012)】；

基金：This work is financially supported by the National Basic Research Program of China (973 Program, 2010CB126100), the National High Technology Research and Development Program of China (863 Program 2011AA10A207), the National Natural Science Foundation of China (grants 21236002), the National Science & Technology Pillar Program and the Fundamental Research Funds for the Central Universities. And we also thank Prof. Bubing Zeng of ECUST for discussions and suggestions.

语种：英文

外文关键词：Benzimidazole; Aldehydes; Schiff bases; Sodium perborate; Oxidation

摘要：A novel strategy for the synthesis of 2-phenylbenzimidazoles with sodium perborate (SPB) as oxidant under mild reaction condition is developed. Excellent chemoselectivity and broad substrate tolerance are the main advantages of this route. (C) 2013 Elsevier Ltd. All rights reserved.