文献类型：期刊文献

英文题名：Thio-Michael addition of thioamides and allenes for the selective construction of polysubstituted 2-arylthiophenes via TBAI/H2O2 promoted tandem oxidative annulation and 1,2-sulfur migration

作者：Han, Teng[1];Luo, Xiaoyan[1]

机构：[1]East China Univ Sci & Technol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2018

卷号：16

期号：37

起止页码：6875

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;EI(收录号：20183905877301);WOS:【SCI-EXPANDED(收录号:WOS:000445637600005)，CCR-EXPANDED(收录号:WOS:000445637600005)】；

基金：This work is supported by the Natural Science Foundation of Shanghai (No. 17ZR1407600).

语种：英文

外文关键词：Hydrocarbons - Addition reactions - Cyclization

摘要：A novel TBAI-catalyzed tandem thio-Michael addition/oxidative annulation of allenes and thioamides for the construction of polysubstituted 2-arylthiophenes under a sulfur migration transformation protocol has been developed. The transition-metal-free protocol achieves the oxidative cyclization reaction of thioamides containing electron-rich substituents with allenes to construct polysubstituted thiophenes selectively by controlling oxidation conditions.