文献类型：期刊文献

英文题名：Rendering cellulose fibers antimicrobial using cationic β-cyclodextrin-based polymers included with antibiotics

作者：Qian, L.[1];Guan, Y.[2,3];Ziaee, Z.[4];He, B.[1];Zheng, A.[2,3];Xiao, H.[1,4]

机构：[1]S China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Peoples R China;[2]E China Univ Sci & Technol, Minist Educ, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai 200237, Peoples R China;[4]Univ New Brunswick, Dept Chem Engn, Fredericton, NB E3B 5A3, Canada

年份：2009

卷号：16

期号：2

起止页码：309

外文期刊名：CELLULOSE

收录：;EI(收录号：20090911927281);WOS:【SCI-EXPANDED(收录号:WOS:000263352900016)】；

基金：The financial supports for this work from SENTINEL NSERC Canada and NSF of Guangdong (Grant no. 06Z002) are gratefully acknowledged.

语种：英文

外文关键词：Cationic beta-cyclodextrin polymers; Antibiotics; Cellulose fiber; Inclusion complexes; Antimicrobial activity; AFM

摘要：Cationic beta-cyclodextrin polymer (CP beta CD) and its complexes with butylparaben and triclosan were reported in this paper. 2D NMR confirmed that the host-guest complexes were formed by including antibiotics inside the cavities of CP beta CDs, which significantly improved the water solubility of the antibiotics. Results of inhibition zones and shaking flask methods of antimicrobial-modified cellulose fibres showed that both antibiotics/CP beta CD complexes had excellent antimicrobial activities when applying on the cellulose fibers whereas triclosan appeared to more effective. Morphology of untreated and treated bacteria revealed by AFM suggested that the antibiotics/CP beta CD complexes inhibited bacteria through affecting the metabolism of the bacteria instead of damaging the cell membrane. Due to the strong electrostatic association, CP beta CD polymers adsorbed on the surface of cellulose fibres almost completely within the range of dosages investigated.