文献类型：期刊文献

中文题名：聚合物刷与生物分子相互作用的研究进展

英文题名：Progress in Interaction between Polymer Brushes and Biomolecules

作者：王思怿[1];郭旭虹[2];陈凯敏[3]

机构：[1]上海化工研究院检测中心,上海200062;[2]华东理工大学化工学院,化学工程联合国家重点实验室,上海200237;[3]上海工程技术大学化学化工学院,上海201620

年份：2016

卷号：29

期号：4

起止页码：359

中文期刊名：功能高分子学报

外文期刊名：Journal of Functional Polymers

收录：CSTPCD;;北大核心:【北大核心2014】；CSCD:【CSCD2015_2016】；

基金：国家自然科学基金(21504052);上海市青年科技英才扬帆计划(15YF1404800)

语种：中文

中文关键词：聚合物刷;生物分子;相互作用;蛋白固定化;酶催化

外文关键词：polymer brush; biomolecule; interaction; protein immobilization; enzymatic catalyst

摘要：聚合物刷是由一端紧密接枝在一个曲面或平面的聚合物链组成的大分子结构。近年来,随着聚合物制备方法和表面修饰技术的不断发展,聚合物刷的应用范围也在不断拓宽,相关研究已成为功能高分子材料领域的热点之一。具有特殊结构和功能的聚合物刷在生物分子固定、蛋白质分离、酶催化、药物控释等方面具有广阔的应用前景。本文综述了聚合物刷与生物分子相互作用及应用的最新研究进展,并展望了今后的发展方向。
Polymer brush is a structure with polymer chains attached with one end to a curved or planar surface. In recent years, with the development of polymer preparation methods and surface modification technology, the application range of polymer brush is continuously expanded. Relevant researches of polymer brush become one of the hotpots in the area of functional polymeric materials. Polymer brushes with unique structure and surface properties become suitable candidates in the application of biomolecule immobilization,protein separation, enzymatic catalyst and controlled drug delivery. In this review,the latest progress in interactions between polymer brushes and biomolecules is systematically described, and some possible directions for further research are forecasted.