文献类型：期刊文献

英文题名：Electrochemical sensing interfaces with tunable porosity for nonenzymatic glucose detection: A Cu foam case

作者：Niu, Xiangheng[1,2];Li, Yuxiu[1,2];Tang, Jie[1,2];Hu, Yangliao[1,2];Zhao, Hongli[3];Lan, Minbo[1,2,4]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Res Ctr Anal & Test, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Inst Appl Chem, Shanghai 200237, Peoples R China;[4]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2014

卷号：51

起止页码：22

外文期刊名：BIOSENSORS & BIOELECTRONICS

收录：;EI(收录号：20133416640759);WOS:【SCI-EXPANDED(收录号:WOS:000326905500004)】；

基金：This study was financially supported by the Science and Technology Commission of Shanghai Municipality (No. 13510710900) and the Fundamental Research Funds for the Central Universities (No. 222201314026). We also acknowledge Dr. Dianyu Qi for BET measurements.

语种：英文

外文关键词：Cu foam; Electrochemical sensing interface; Glucose; Nonenzymatic sensor; Porous structure

摘要：It is widely thought in electro-biochemical analysis that the sensing interfaces play a key role in the enzymeless detection of biomolecules like glucose, ascorbic acid, dopamine and uric acid. On the way to maximize the anti-poisoning sensitivity of nonenzymatic electrochemical glucose sensors as well as achieve favorable selectivity, we propose here a porous interface fabricated by a facile but effective approach for glucose monitoring in alkaline media containing dissolved oxygen. The sensing interface based on porous Cu foams is directly formed on a homemade disposable screen-printed carbon electrode (SPCE) substrate by electrodeposition assisted with hydrogen evolution simultaneously, and its porosity can be easily tailored through adjusting deposition conditions for the optimal electrocatalytic oxidation of glucose molecules. SEM and BET studies show that the generated Cu foam possesses robust hierarchical porous architectures with greatly enhanced surface area and pore volume, beneficial for the unimpeded mobility of glucose and reaction products. Cyclic voltammetric tests indicate that a diffusion-controlled glucose electro-oxidation reaction occurs at the Cu foam electrode at around +0.35 V vs. Ag/AgCl in 0.1 M NaOH. Chronoamperometric results obtained under optimized conditions reveal that the proposed sensor exhibits desired poison resistance ability in the presence of chloride ions and significant selectivity to glucose, providing fascinating sensitivities of 2.57 and 1.81 mA cm(-2) mM(-1) for glucose in the linear concentration ranges of 2-80 mu M and 0.1-5 mM, respectively. The limit of detection is calculated to be as low as 0.98 mu M according to the signal-to-noise ratio of three. In addition, the fabricated sensing interface shows attractive reproducibility (RSD of 5.1% and 7.0% for 15 repeated measurements on a sensor and for measurements on 15 prepared sensors, respectively) and outstanding long-term stability (less than 5% loss in sensitivity over 1 month) for glucose detection. The application of the Cu foam based sensor for monitoring glucose in practical samples is also successfully demonstrated. 2013 Elsevier B.V. All rights reserved.