文献类型：期刊文献

英文题名：Construction and Characterization of a Novel Sustained-Release Delivery System for Hydrophobic Pesticides Using Biodegradable Polydopamine-Based Microcapsules

作者：Zou, Aihua[1,2];Yang, Ying[1,2];Cheng, Jiagao[3];Garamus, Vasil M.[4];Li, Na[5,6]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Appl Chem, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[4]Helmholtz Zentrum Geesthacht, Ctr Mat & Coastal Res, D-21502 Geesthacht, Germany;[5]Natl Ctr Prot Sci Shanghai, Shanghai 201210, Peoples R China;[6]Shanghai Inst Biochem & Cell Biol, Shanghai 201210, Peoples R China

年份：2018

卷号：66

期号：25

起止页码：6262

外文期刊名：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

收录：;EI(收录号：20182305287532);WOS:【SCI-EXPANDED(收录号:WOS:000436910400002)】；

基金：The present study was supported by grants from the National Key Research and Development Plan (2017YFD0200306), the National Natural Science Foundation of China (31200617), and Knowledge Innovation Program of CAS (Grant 2013KIP103).

语种：英文

外文关键词：lambda-cyhalothrin; pyrethroids; microcapsule; polydopamine; self-polymerization; sustained release

摘要：Microcapsule formulations have been highly desirable and widely developed for effective utilization of pesticides and environmental pollution reduction. However, commercial and traditional microcapsule formulations of lambda-cyhalothrin (LC) were prepared by complicated synthesis procedures and thereby specific organic solvents were needed. In this work, LC was encapsulated into versatile, robust, and biodegradable polydopamine (PDA) microcapsules by self-polymerization of dopamine. LC-loaded PDA microcapsules were characterized by transmission electron microscopy (TEM), small-angle X-ray scattering (SAXS), and thermogravimetric analysis measurements (TGA). LC-loaded PDA microcapsules have uniform morphology with nanoscale, decent LC loading content (>50.0% w/w), and good physicochemical stability and sustained release properties. The bioassay against housefly (Musca domestica) showed that the bioactivity and long-term efficiency of LC-loaded PDA microcapsules was superior to that of the commercial formulation. All of these results demonstrated that LC-loaded PDA microcapsules could be applied as a commercial LC microcapsule formulation with fewer environmental side effects and higher effective delivery.