文献类型：期刊文献

英文题名：Highly selective fluorescent chemosensor with red shift for cysteine in buffer solution and its bioimage: symmetrical naphthalimide aldehyde

作者：Duan, Liping[1];Xu, Yufang[1];Qian, Xuhong[1];Wang, Fang[1];Liu, Jianwen[1];Cheng, Tanyu[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2008

卷号：49

期号：47

起止页码：6624

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000260944900006)】；

基金：This work is supported by the National Natural Science Foundation of China (20536010), Program of Shanghai Subject Chief Scientist and Shanghai Leading Academic Discipline Project(13507), and the National High Technology Research and Development Program of China (863 Program 2006AA10A201).

语种：英文

摘要：A new fluorescent probe 1. N-butyl-4, 5-(p-aldehyde)phenyl-1,8-naphthalimide, was designed and synthesized for the determination of the cysteine (Cys). Upon addition of Cys, the emission of 1 was enhanced with about 25 nm red-shift in the emission maximum (from 455 to 480 nm), accompanied with the fluorescent color change from blue to cyan, which was attributed to the reaction of the aldehyde groups in 1 with cysteine to form very stable thiazolidines derivative. Compound 1 was highly selective for cysteine detection without the interference of other amino acids and can be used for bioimaging of Cys. (C) 2008 Published by Elsevier Ltd.