文献类型：期刊文献

英文题名：Synthesis of axially chiral gold complexes and their applications in asymmetric catalyses

作者：Sun, Yin-Wei[1,2];Xu, Qin[1,2];Shi, Min[1,2,3]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2013

卷号：9

起止页码：2224

外文期刊名：BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000327702700002)】；

基金：Financial support from the Shanghai Municipal Committee of Science and Technology (08dj1400100-2), the Fundamental Research Funds for the Central Universities, the National Basic Research Program of China (973)-2010CB833302, the Fundamental Research Funds for the Central Universities, and the National Natural Science Foundation of China (21072206, 21121062, 21121062, 20902019, 20472096, 20872162, 20672127, 20732008, 20821002, and 20702013) are gratefully acknowledged.

语种：英文

外文关键词：asymmetric gold catalysis; chiral Au catalysts; gold-pi interaction; NHC gold complex

摘要：Several novel chiral N-heterocyclic carbene and phosphine ligands were prepared from (S)-BINOL. Moreover, their ligated Au complexes were also successfully synthesized and characterized by X-ray crystal diffraction. A weak gold-pi interaction between the Au atom and the aromatic ring in these gold complexes was identified. Furthermore, we confirmed the formation of a pair of diastereomeric isomers in NHC gold complexes bearing an axially chiral binaphthyl moiety derived from the hindered rotation around C-C and C-N bonds. In the asymmetric intramolecular hydroamination reaction most of these chiral Au(I) complexes showed good catalytic activities towards olefins tethered with a NHTs functional group to give the corresponding product in moderate yields and up to 29% ee.