文献类型：期刊文献

英文题名：A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

作者：Guo, Ting[1];Cui, Lei[1];Shen, Jiaoning[1];Wang, Rui[1];Zhu, Weiping[1];Xu, Yufang[1];Qian, Xuhong[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2013

卷号：49

期号：18

起止页码：1862

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000314650100025)】；

基金：The authors are grateful for the financial support from the State Key Program of National Natural Science of China (21236002), the National Basic Research Program of China (2010CB126100), the National High Technology Research and Development Program of China (2011AA10A207), the Fundamental Research Funds for the Central Universities.

语种：英文

摘要：A novel dual-emission fluorescence probe has been developed for specific and sensitive detection of hypochlorite (ClO-). Upon addition of ClO-, significant changes in fluorescence emission intensity at two discrete wavelengths were observed. Meanwhile OONO- led to only a single-channel fluorescence enhancement. This feature makes it a clear advantage in distinguishing ClO-, RNS from other ROS.