文献类型：期刊文献

英文题名：Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler

作者：Yang, Ke[1,2];Hoskins, Peter R.[2];Corner, George A.[2];Xia, Chunming[1,3];Huang, Zhihong[2]

机构：[1]East China Univ Sci & Technol, Sch Mech & Power Engn, Shanghai 200237, Peoples R China;[2]Univ Dundee, Sch Sci & Engn, Dundee DD1 4HN, Scotland;[3]Shanghai Univ Engn Sci, Sch Mech & Automot Engn, Shanghai 201620, Peoples R China

年份：2023

卷号：13

期号：1

外文期刊名：APPLIED SCIENCES-BASEL

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000909268800001)】；

语种：英文

外文关键词：wall shear stress; stenosis phantom; plane wave; vector Doppler

摘要：Wall shear stress (WSS) plays an important role in the formation, growth, and rupture of atherosclerotic plaques in arteries. This study measured WSS in diseased carotid artery phantoms with degrees of stenosis varying from 0 to 60% with both steady and pulsatile flow. Experiments were performed using in silico and real flow phantoms. Blood velocities were estimated using plane wave (PW) vector Doppler. Wall shear stress was then estimated from the velocity gradient near the wall multiplied by the viscosity of a blood-mimicking fluid. The estimated WSS using the in silico phantom agreed within 10% of the ground-truth values (root-mean-square error). The phantom experiment showed that the mean WSS and maximum WSS increased with the increasing degree of stenosis. The simulation and experiment results provide the necessary validation data to give confidence in WSS measurements in patients using the PW vector Doppler technique.