文献类型：期刊文献

英文题名：Regio- and diastereoselective construction of 1′,2′-(dihydrospiro[indoline-3,3′-pyrrol]-2′-yl)acrylates through phosphine-catalyzed [4+1] annulation of Morita-Baylis-Hillman carbonates with oxindole-derived α, β-unsaturated imines

作者：Lei, Yu[1,2];Zhang, Xiao-Nan[1,2];Yang, Xue-Yan[1,2];Xu, Qin[1,2];Shi, Min[1,2,3]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2015

卷号：5

期号：61

起止页码：49657

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20152400935556);WOS:【SCI-EXPANDED(收录号:WOS:000355989400080)】；

基金：We are grateful for the financial support from the National Basic Research Program of China (973)-2015CB856603, and the National Natural Science Foundation of China (20472096, 21372241, 21361140350, 20672127, 21421091, 21372250, 21121062, 21302203 and 20732008).

语种：英文

外文关键词：Phosphorus compounds - Amides - Stereoselectivity - Rate constants - Catalysis - Salts

摘要：Phosphine-catalyzed [4 + 1] annulation of Morita-Baylis-Hillman (MBH) carbonates with oxindole-derived alpha, beta-unsaturated imines has been developed, giving the corresponding 1',2'-(dihydrospiro[indoline-3,3'-pyrrol]-2'-yl)acrylates in moderate to good yields and diastereoselectivities under mild conditions.