文献类型：期刊文献

中文题名：两种噁二唑类化合物对蔬菜害虫的生物活性研究

英文题名：Biological Activities of Two Oxadiazole Derivatives against Vegetable Pest Insects

作者：黄青春[1];曹松[1];卓军[1];钱旭红[1]

机构：[1]华东理工大学药物化工研究所,上海200237

年份：2005

卷号：7

期号：1

起止页码：77

中文期刊名：农药学学报

外文期刊名：Chinese Journal of Pesticide Science

收录：CSTPCD;;CSCD:【CSCD2011_2012】；

基金：上海市科委攻关项目(编号:034319245);上海市重点学科资助.

语种：中文

中文关键词：噁二唑类化合物;害虫;生物活性;拒食作用

外文关键词：oxadiazole derivatives; pest insect; biological activity; antifeedant action

摘要：对两种新型口恶二唑类化合物 2 叔丁基 4 氯 5 [5 (4 氯苯基) 2 (1,3,4 口恶二唑 ) 甲氧基 ] 3(2H)哒嗪酮(HL 19)和 2,5 二(5 氟 2,4 二氯苯基) 1,3,4口恶二唑 (HL 25)对蔬菜害虫的生物活性以及作用方式的差异性进行了室内比较和田间药效试验。HL 19主要抑制菜青虫Pierisrapae等 6种鳞翅目害虫幼虫的生长发育,几乎不杀死试虫,其中粘虫Mythimnaseparata对其最敏感,IC50为 0.11mmol/L;HL 19还具有一定的拒食作用,但拒食活性随试虫龄期的增大而降低,且都稍低于同浓度印楝素,对粘虫和菜青虫的非选择性拒食活性达 65%以上,对 2龄粘虫的选择性拒食活性为 2.43μg/cm2。HL 25能够杀死试虫,但作用速度亦较慢,无拒食活性,粘虫对其亦最敏感,LC50为 0.06mmol/L。HL 19和HL 25对豆蚜Aphiscraccivora成虫的LC50分别为 0.13mmol/L和 0.24mmol/L。田间试验表明,HL 19和HL 25对菜青虫的防治效果可达 86. 4%和 74. 6%。HL 19和HL 25对害虫具有不同的作用特性。
The activity of two novel 1,3,4-oxadiazoles containing a 2H-pyridazin-3-one group (HL-19) and symmetrical benzene group (HL-25) were taken into investigation on vegetable pest insects by laboratory assays and field tests. The results showed that HL-19 could strongly inhibit the growth and development of the six lepidopteran larvae such as Pieris rapae. Mythimna separata larvae were most sensitive with IC_(50 ) 0.11 mmol/L. HL-19 also exhibited considerable antifeedant activity (against) the larvae of M. separata, P. rapae, and Plutella xylostella, which were decreased with the growth of insects and (always) slightly inferior to the action of azadirachtin, the non-choice antifeeding activity of HL-19 against M. separata and P. rapae larvae exceeded 65% and its choice antifeeding activity against 2nd instar larvae of M. separata was 2.43 μg/cm^(2 ). However, HL-25 (possessed) slow lethal activity against the lepidopteran larvae and lost antifeedant action, the highest activity was (against) (M. separata) larvae with LC_(50 ) 0.06 mmol/L. HL-19 and HL-25 could kill the apterous Aphis (craccivora) adult with LC_(50) 0.13 mmol/L and 0.24 mmol/L. Furthermore, field tests of HL-19 and HL-25 against P. rapae obtained 86.4% and 74.6% control efficiency respectively.