文献类型：期刊文献

英文题名：HClO4-SiO2 as an efficient and recyclable catalyst for the synthesis of amide derivatives

作者：Song, Weibin[1]; Ma, Lei[1]; Hu, Lihong[1,2]

机构：[1] School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 20023, China; [2] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

年份：2011

卷号：41

期号：21

起止页码：3186

外文期刊名：Synthetic Communications

收录：EI(收录号：20242616553690)

语种：英文

外文关键词：Alkylation - Catalysts - Chlorine compounds - Condensation - Silica - Sulfur compounds

摘要：An efficient and clean procedure for amide alkylation is reported by direct condensation of equimolar amounts of benzylic and allylic alcohols with primary amides in the presence of silica perchloric acid (HClO4-SiO 2). The direct condensation of secondary benzylic and allylic alcohols with benzamide, sulfonamide, 2-furamide, cinnamamide, and acrylamide has been achieved to afford the corresponding amide in excellent yields. The convenient, recyclable, and excellent yields of products are attractive features of this reaction. Copyright ? 2011 Taylor & Francis Group, LLC.