文献类型：期刊文献

英文题名：Sodium silicate bonded borate glass scaffolds for tissue engineering

作者：Liang, Wen[1]; Wang, Meng[1]; Day, Delbert E.[2]; Rüssel, Christian[3]

机构：[1]E China Univ Sci & Technol, Res Inst Biomat, Shanghai 200237, Peoples R China;[2]Univ Missouri, Mat Res Ctr, Rolla, MO 65401 USA;[3]Univ Jena, Otto Schott Inst, D-6900 Jena, Germany

年份：2007

卷号：42

期号：24

起止页码：10138

外文期刊名：JOURNAL OF MATERIALS SCIENCE

收录：;EI(收录号：20074110864222);WOS:【SCI-EXPANDED(收录号:WOS:000249980100035)】；

语种：英文

外文关键词：Borate minerals - Glass - Hydroxyapatite - Microspheres - Porosity - Porous materials - Scaffolds - Silicate minerals - Size distribution - Sodium silicate process - X ray diffraction

摘要：Borate and silicate glass particles and microspheres with size distributions in the range of approximately 100-400 micron were loosely compacted and bonded by sodium silicate solution to prepare resorbable, porous glass constructs with porosity 30-50%. Conversion of the binding borate glass to hydroxyapatite was investigated by measuring the weight loss of the constructs in a solution of 0.25 M K2HPO4 with a pH value of 9.0 at 37 degrees C, as a function of time. Almost full conversion of the borate glass to hydroxyapatite was achieved in less than 6 days. X-ray diffraction revealed an initially amorphous product that subsequently crystallized to hydroxyapatite.