文献类型：期刊文献

中文题名：铁炭复合磁靶向缓释药物载体材料的制备——制备条件对铁炭复合材料磁性能的影响

英文题名：Preparation of magnetic targeting and controlled desorpting iron-carbon powder as drug carrier

作者：马垠智[1];曹宏明[1];黄广建[2];吴秋芳[1];张海英[1];於定华[1]

机构：[1]华东理工大学国家超细粉末工程研究中心,上海200237;[2]复旦大学附属华山医院,上海200040

年份：2004

卷号：35

期号：4

起止页码：423

中文期刊名：功能材料

外文期刊名：Journal of Functional Materials

收录：CSTPCD;;EI(收录号：2004468459223);Scopus;北大核心:【北大核心2000】；CSCD:【CSCD2011_2012】；

基金：国家科技部重大基础研究前期研究专项资助项目(2002CCA01100)

语种：中文

中文关键词：铁炭颗粒;磁靶向;缓释

外文关键词：Activated carbon;Controlled drug delivery;High temperature effects;Hydrogen;Iron oxides;Magnetic properties;Powder coatings;Reduction;Silica

摘要：　研究了一种新型铁炭复合磁靶向缓释药物载体材料的制备方法。用医用活性炭和纳米四氧化三铁粉末球磨制成铁炭复合材料,该材料表面包硅处理后用氢气高温还原,得到可以作为磁靶向缓释药物载体的铁炭复合材料。考察了制备过程中的包硅和还原工艺条件对铁炭复合材料磁性能的影响。
Preparation of iron-carbon magnetic powder for delivering chemotherapeutic drug was described. The particles were prepared by activated carbon and Fe3O4 powder's milling, being coated by SiO2 and reduction under high temperature with H2. The influence of SiO2 coating content, reduction time and reduction temperature on magnetic characteristics of the iron-carbon powder was studied.