文献类型：期刊文献

英文题名：Copper- and Nickel-Catalyzed Cross-Coupling Reaction of Monofluoroalkenes with Tertiary, Secondary, and Primary Alkyl and Aryl Grignard Reagents

作者：Shi, Hongyan[1];Dai, Wenpeng[1];Wang, Biyun[1];Cao, Song[1,2]

机构：[1]ECUST, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

年份：2018

卷号：37

期号：3

起止页码：459

外文期刊名：ORGANOMETALLICS

收录：;EI(收录号：20180704802525);WOS:【SCI-EXPANDED(收录号:WOS:000425193000025)，CCR-EXPANDED(收录号:WOS:000425193000025)】；

基金：We are grateful for financial support from the National Natural Science Foundation of China (Grant Nos. 21472043 and 21272070).

语种：英文

外文关键词：Catalysis - Catalysts - Copper - Nickel

摘要：A highly efficient cross-coupling reaction of monofluoroalkenes with tertiary, secondary, and primary alkyl and aryl Grignard reagents in the presence of a catalytic amount of copper or nickel catalyst, respectively, has been developed. The reactions proceeded smoothly at room temperature, providing (E)-alkene isomers in moderate to high yields. Plausible mechanisms of the Ni-catalyzed coupling reaction of monofluoroalkene with Grignard reagents are suggested.