文献类型：期刊文献

英文题名：Axially Chiral Phenanthroline Ligand-Enabled Copper-Catalyzed Enantioselective Arylation of Azonaphthalenes with Arylboronic Acids

作者：Wang, Ruiyu;Cen, Shouyi[1];Zhang, Zhipeng[1]

机构：[1]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn,Key Lab Adv Mat, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn,Joint Int Res Lab Precis Chem, Shanghai 200237, Peoples R China

年份：2025

卷号：36

期号：06

起止页码：695

外文期刊名：SYNLETT

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001335584200002)，CCR-EXPANDED(收录号:WOS:001335584200002)】；

基金：We acknowledge the provision of financial support by the National Natural Science Foundation of China (22371072, 21702059) and the Fundamental Research Funds for the Central Universities (222201717003, JKJ01231652, JKVJ1241010, SLJ13233303)

语种：英文

外文关键词：asymmetric catalysis; phenanthroline ligands; copper catalysis; azonaphthalenes; arylboronic acids; biaryls

摘要：An axially chiral phenanthroline ligand bearing two BINOL units was found to be capable of promoting the copper-catalyzed enantioselective arylation of 2-azonaphthalenes with arylboronic acids. This atroposelective Michael-type addition affords a range of enantioenriched axially chiral biaryl compounds in synthetically useful yields with enantiomeric ratios of up to 91.5:8.5.