文献类型：期刊文献

英文题名：Influences of sodium tantalite submicro-particles in polyetheretherketone based composites on behaviors of rBMSCs/HGE-1 cells for dental application

作者：Ren, Lishu[1];Tang, Songchao[1];Shen, Xuening[1];Gao, Chao[1];Jung, Yun Kyung[3];Wang, Dongliang[2];He, Axiang[4];Yang, Lili[4];Shin, Jung-Woog[3];Wei, Jie[1]

机构：[1]East China Univ Sci & Technol, Key Lab Ultrafine Mat, Minist Educ, Shanghai 200237, Peoples R China;[2]Shanghai Jiao Tong Univ, Xin Hua Hosp, Dept Orthoped Surg, Sch Med, 1665 Kongjiang Rd, Shanghai 200092, Peoples R China;[3]Inje Univ, Sch Biomed Engn, Inje Ro 197, Gimhae 50834, Gyeongnam, South Korea;[4]Second Mil Med Univ, Changzheng Hosp, Dept Orthopaed Surg, Shanghai 200003, Peoples R China

年份：2020

卷号：188

外文期刊名：COLLOIDS AND SURFACES B-BIOINTERFACES

收录：;EI(收录号：20195207926686);WOS:【SCI-EXPANDED(收录号:WOS:000527305100032)】；

基金：This work was supported by the National Natural Science Foundation of China (81771990 and 81572194), the Key Medical Program of Science and Technology Development of Shanghai (19441906100, 17441900600 and 17441902000), and the National key research and development program (2016YFC1102100).

语种：英文

外文关键词：Sodium tantalite; Polyetheretherketone; Composites; Surface; Submicro-Structures; Cells responses

摘要：Dental implanted materials require excellent mechanical properties, biocompatibility as well as integration with bone tissue and gingival tissue to achieve early loading and long-term stability. In this study, cubic shape sodium tantalite (ST) submicro-particles with the size of around 180 nm were synthesized by a hydrothermal method, and ST/polyetheretherketone (PEEK) composites (TPC) with ST content of 20w% (TPC20) and 40w% (TPC40) were prepared by melting blend. The results showed that the compressive strength, thermal properties, surface roughness, hydrophilicity and surface energy as well as adsorption of proteins on TPC40 were also significantly enhanced compared with TPC20 and PEEK. Moreover, the responses (adhesion and proliferation as well as differentiation) of rat bone marrow mesenchymal stem cells (rBMSCs), and responses (adhesion, and proliferation) of human gingival epithelial (HGE-1) cells to TPC40 were significantly promoted compared with TPC20 and PEEK. The results demonstrated that ST content in TPC had remarkable effects on the surface properties, which played key roles in stimulating the responses of both rBMSCs and HGE-1 cells. TPC40 with increased surface properties and excellent cytocompatibility might have great potential as an implanted material for dental application.