文献类型：期刊文献

英文题名：Design, Multicomponent Synthesis, and Bioactivities of Novel Neonicotinoid Analogues with 1,4-Dihydropyridine Scaffold

作者：Zhang, Wenwen[2];Yang, Xiaobao[2];Chen, Weidong[2];Xu, Xiaoyong[2];Li, Lu[2];Zhai, Hongbin[1];Li, Zhong[2]

机构：[1]Chinese Acad Sci, Shanghai Inst Organ Chem, Lab Modern Synthet Organ Chem, Shanghai 200032, Peoples R China;[2]E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2010

卷号：58

期号：5

起止页码：2741

外文期刊名：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000275087600021)】；

基金：This work is-as financially supported by National Key Project for Basic Research (2003CB114405), National Natural Science Foundation of China (2087203), Program for New Century Excellent Talents in University (NCET070284), and National High Technology Research and Development Program of China (863 Program, 2006AA10A201). We also appreciate partial support from the Shanghai Foundation of Science and Technology (064319022, 08391911600), Shanghai Leading Academic Discipline Project, Project 13507 and 111 Project (No. 1307023).

语种：英文

外文关键词：1,4-Dihydropridine; MCRs; biological activity

摘要：Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance pi-pi stacking. The synthesized compounds were identified by H-1 NMR, C-13 NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid (Aphis craccivora).