文献类型：期刊文献

中文题名：De novo biosynthesis of a vinblastine precursor in Pichia pastoris

作者：Jiaming Yu[1];Dongyuan Lv[1];Lixin Zhang[1]

机构：[1]State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology,Shanghai,200237,China

年份：2023

卷号：8

期号：2

起止页码：300

中文期刊名：Synthetic and Systems Biotechnology

外文期刊名：合成和系统生物技术（英文）

收录：Scopus;CSCD:【CSCD2023_2024】；PubMed;

语种：英文

中文关键词：products.;synthesis;preparation;

摘要：Plant natural products have been widely used in medicine,food,and cosmetics.Of a particular note,many natural products from Cathar-anthus roseus have important biological activities and medicinal value^([1]),with vinblastine as one of the most effective drugs for cancer treatment^([2]).Due to difficulties in chemical synthesis of such complex structures,plant extraction is still the major method for large-scale preparation of plant natural products.