文献类型：专利

英文题名：Preparation of p-methoxyphenylacetonitrile involves reacting p-methoxybenzyl alcohol and thionyl chloride in solvent, and reacting obtained intermediate benzyl chloride and sodium cyanide in presence of phase transfer catalyst

作者：WU F;ZHAO M;YANG B;YE L;GU X;XIAO S;SAIDALIMU Y

机构：[1]UNIV EAST CHINA SCI&TECHNOLOGY

申请号：CN101774946-A

申请日：2009-12-15

公开日：2010-07-14

语种：英文

收录：DERWENT

摘要：NOVELTY - A p-anisaldehyde and reducing agent are reacted in presence of normal reagent, to obtain a p-methoxybenzyl alcohol. The p-methoxybenzyl alcohol and thionyl chloride are reacted in solvent, to obtain an intermediate benzyl chloride. The obtained intermediate benzyl chloride and sodium cyanide are reacted in presence of phase transfer catalyst under alkali conditions, to obtain p-methoxyphenylacetonitrile. USE - Preparation of p-methoxyphenylacetonitrile. ADVANTAGE - The p-methoxyphenylacetonitrile is prepared with yield of 85% or more.