文献类型：期刊文献

英文题名：Oxidative Alkenylation/Annulation of Benzimidates via Ruthenium(II)-Catalyzed C-H Activation to Generate 3-Methyleneisoindolin-1-ones

作者：Li, Xing Guang[1,2];Sun, Min[1,2];Liu, Kai[1,2];Liu, Pei Nian[1,2]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2015

卷号：357

期号：2-3

起止页码：395

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000351221700014)，CCR-EXPANDED(收录号:WOS:000351221700014)】；

基金：This work was supported by the National Natural Science Foundation of China (Project Nos. 21172069, 21372072 and 21190033), the Science Fund for Creative Research Groups (21421004), NCET (NCET-13-0798), the Basic Research Program of the Shanghai Committee of Sci. & Tech. (Project No. 13M1400802) and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：alkenes; annulation; cascade reaction; C-H activation; ruthenium

摘要：A novel ruthenium-catalyzed oxidative alkenylation/annulation cascade reaction is described for synthesizing 3-methyleneisoindolin-1-ones. In the protocol, the N-H imidate is applied efficiently as a directing group in ruthenium-catalyzed C-H activation, generating various 3-methyleneisoindolin-1-ones with high regio- and stereoselectivity in moderate to good yields.