文献类型：期刊文献

英文题名：A Metal-free Approach to 3-Aryl-3-hydroxy-2-oxindoles by Treatment of 3-Acyloxy-2-oxindoles with Diaryliodonium Salts

作者：Li, Xiaokang[1];Ni, Wei[1];Mao, Fei;Wang, Wei[1,2];Li, Jian[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

年份：2016

卷号：11

期号：2

起止页码：226

外文期刊名：CHEMISTRY-AN ASIAN JOURNAL

收录：;EI(收录号：20155001658009);WOS:【SCI-EXPANDED(收录号:WOS:000369064400010)】；

基金：Financial support of this research provided by the National Natural Science Foundation of China (Grants 21222211, 21372001, 91313303 and 21372073), the Program for New Century Excellent Talents in University (Grant NCET-12-0853), "Shu Guang" project supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation (Grant 14SG28), and the Fundamental Research Funds for the Central Universities is gratefully acknowledged.

语种：英文

外文关键词：3-acyloxy-2-oxindoles; 3-aryl-3-hydroxy-2-oxindole; arylation; diaryliodonium salt; metal-free

摘要：A mild, metal-free approach has been realized for the facile construction of highly valuable 3-(hetero)aryl-3-hydroxy-2-oxindoles. Direct arylations of 3-acyloxy-2-oxindoles with diaryliodonium salts as arylation reagents are implemented in the presence of K2CO3 at room temperature without using an organometallic promoter to deliver an array of 3-(hetero)aryl-3-hydroxy-2-oxindoles in good yields.