文献类型：期刊文献

英文题名：Biomolecular adsorption behavior on spherical carbon aerogels with various mesopore sizes

作者：Long, Donghui[1];Zhang, Rui[1];Qiao, Wenming[1];Zhang, Liang[1];Liang, Xiaoyi[1];Ling, Licheng[1]

机构：[1]E China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China

年份：2009

卷号：331

期号：1

起止页码：40

外文期刊名：JOURNAL OF COLLOID AND INTERFACE SCIENCE

收录：;EI(收录号：20090211855267);WOS:【SCI-EXPANDED(收录号:WOS:000263038100008)】；

基金：This work was supported by National Science foundation of China (50730003 and 50672025) and 973 grant (2006CB600907).

语种：英文

外文关键词：Spherical carbon aerogel; Sol-gel; Mesopore; Biomolecule; Adsorption; Adsorption rate; Adsorption isotherm

摘要：Spherical carbon aerogels (SCAs) with controlled particle size and mesopore size were synthesized by an emulsified sol-gel polymerization of phenol, melamine and formaldehyde. The adsorption rate and capacity of biomolecules with different molecular dimensions, including L-phenylalanine (Phe), vitamin B-12 (VB), alpha-chymotrypsin (Chy) and bovine serum albumin (BSA) onto SCAs were investigated. The mesopore size can be easily tuned in the range from 5 to 10 nm by simply adjusting catalyst concentration in the initial solution and the spherical particle size can be controlled in 50-500 mu m by changing stirring speed. The as-prepared SCAs have high specific surface area (>600 m(2)/g) and large pore volume (>1 cm(3)/g). The hardness of SCAs is ca. 10 times as large as that of commercial spherical activated carbon particles. The adsorption rate of VB is strongly depended on the mesopore size and particle size, and show an increasing tread with the increase of mesopore size and the decrease of particle size. For small molecule Phe, the specific Surface area is key factor to determine the adsorption capacity, but the adsorption capacity of large molecules (VB, Chy and BSA) is dependent on the pore size of SCAs, which should be suitably larger than the molecule size of biomolecules. (C) 2008 Elsevier Inc. All rights reserved.