文献类型：期刊文献

英文题名：An ultrasensitive fluorescent probe for hydrazine detection and its application in water samples and living cells

作者：Guo, Shao-Hua[1,2];Guo, Zhi-Qian[1,2];Wang, Cheng-Yun[1];Shen, Yongjia[1,2];Zhu, Wei-Hong[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2019

卷号：75

期号：18

起止页码：2642

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000466451800004)】；

基金：The authors are grateful to financial support from the Natural Science Foundation of Shanghai (16ZR1408000) and the Fundamental Research Funds for the Central Universities (WJ1814055).

语种：英文

外文关键词：Ultrasensitive; Hydrazine; Real water; Bioimaging

摘要：Hydrazine, as a strong reducing agent, has been extensively used in many industrial manufactures. However, it is a potential human carcinogen and an environmental contaminant due to its high toxicity. Therefore, developing an ultrasensitive method for determining hydrazine in real water and biosystems is of great significance. Herein, based on coumarin dye, a turn-on fluorescent probe Cou-1-N2H4, which contains an acetyl group as the trigger unit and the fluorescence quencher, is developed. The probe can achieve a rapid (3min) and colorimetric sensing detection for hydrazine with an extremely low limit detection (11.9 nM or 0.38 ppb). More importantly, the practical utilities of probe have been successfully proved through quantitative N2H4 detection in environmental water samples and bioimaging of N2H4 in living cells. (C) 2019 Elsevier Ltd. All rights reserved.