文献类型：期刊文献

英文题名：One-Pot Synthesis of 4-Substituted 1,5-Diaryl-1H-pyrazole-3-carboxylic Acids via a MeONa/LiCl-Mediated Sterically Hindered Claisen Condensation-Knorr Reaction-Hydrolysis Sequence

作者：Jiang, Jian-An[1];Du, Cai-Yan[1];Gu, Chun-Hui[1];Ji, Ya-Fei[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2012

期号：20

起止页码：2965

外文期刊名：SYNLETT

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000312487700020)，CCR-EXPANDED(收录号:WOS:000312487700020)】；

基金：The authors thank the National Natural Science Foundation of China (Project No. 21176074) for financial support.

语种：英文

外文关键词：MeONa/LiCl; sterically hindered Claisen condensation; Knorr reaction; 4-substituted 1,5-diaryl-1H-pyrazole-3-carboxylic acids; "one-pot" synthesis

摘要：A "one-pot" synthesis of 4-substituted 1,5-diaryl-1H-pyrazole-3-carboxylic acids was first reported in moderate to good yields. This concise procedure, featuring efficiency and green chemistry, was composed of MeONa/LiCl-mediated sterically hindered Claisen condensation, Knorr reaction and hydrolysis.