文献类型：期刊文献

英文题名：Intergenerational relationship between parental famine exposure and offspring's obesity risks

作者：Hu, Kai[1];Cui, Aoyuan[2];Zhang, Xiao[3]

机构：[1]East China Univ Sci & Technol, Sch Social & Publ Adm, Dept Sociol, Shanghai, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Univ Chinese Acad Sci, CAS Key Lab Nutr Metab & Food Safety, Shanghai, Peoples R China;[3]Tianjin Normal Univ, Coll Life Sci, Tianjin Key Lab Conservat & Utilizat Anim Divers, Tianjin, Peoples R China

年份：2024

卷号：78

期号：3

起止页码：160

外文期刊名：JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

收录：;WOS:【SSCI(收录号:WOS:001107630100001)，SCI-EXPANDED(收录号:WOS:001107630100001)】；

语种：英文

外文关键词：Obesity; Famine exposure; Epigenetics; Intergeneration; BMI

摘要：BackgroundThe intergenerational relationship between parental famine exposure and the obesity risks of offspring has not been well studied.MethodsUsing a cohort of 3654 respondents whose parents were born between 1950 and 1964 from the national data of the China Family Panel Studies, this study examines the associations between parental exposure to the 1959-1961 Chinese famine and offspring's body mass index (BMI). A cross-sectional difference-in-difference design was used to estimate the effects of parental famine exposures on offspring's BMI by exploiting temporal variations in the duration and period of famine across the parental birth cohorts between 1950 and 1964, and geographical variations in the famine severity at the province level.ResultsAfter adjusting individual characteristics and province-level fixed effects, we found that parental famine exposures in the preschool and school-age stages were associated with an increased BMI of offspring while there was not a significant association between prenatal famine exposure and offspring's BMI. The stratified analyses further show that the effects of parental famine exposure did not follow the same trajectory in subgroups.ConclusionsFamine experiences of parents were associated with increased BMI of offspring, suggesting an intergenerational impact of severe malnutrition on obesity risks.