文献类型：期刊文献

英文题名：Allicin impacts the susceptibility of Spodoptera exigua to nucleopolyhedrovirus

作者：Wang, Jin-Yan[1,2];Jiang, Jie-Xian[2];Fan, Neng-Neng[2];Wu, Hua-Wu[2];Ji, Xiang-Yun[2];Wan, Nian-Feng[3];Hou, You-Ming[1]

机构：[1]Fujian Agr & Forestry Univ, State Key Lab Ecol Pest Control Fujian & Taiwan Cr, Key Lab Biopesticide & Chem Biol,Minist Educ & Fuj, Minist Educ & Minist,Minist & Prov Joint Innovat C, Fuzhou 350002, Peoples R China;[2]Shanghai Acad Agr Sci, Shanghai Key Lab Protected Hort Technol Ecoenviron, Shanghai 201403, Peoples R China;[3]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2025

卷号：98

期号：2

起止页码：747

外文期刊名：JOURNAL OF PEST SCIENCE

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001310430900001)】；

基金：This study was sponsored by Shanghai Sailing Program (Grant No. 21YF1441100); SAAS Program for Excellent Research Team (Grant No. 2022[017]), and the National Ten Thousand Plan-Young Top Talents of China

语种：英文

外文关键词：Allicin; Spodoptera exigua; Spodoptera exigua multiple nucleopolyhedrovirus; RNA-Seq; RNA interference

摘要：Plant secondary metabolites are crucial in affecting the interactions between insect herbivores and entomoviruses. However, there is limited knowledge regarding the impact of such metabolites on the susceptibility of insect herbivores to entomoviruses. In this study, we adopted the allicin, caterpillars (Spodoptera exigua) and nucleopolyhedrovirus (SeMNPV) as a system, and found that allicin significantly increased the mortality of S. exigua larvae infected with SeMNPV by 36.03-59.45% when infected with the virus at a concentration of 2.12 x 10(3) OBmL(-1). Furthermore, NPV-infected larvae together treated with allicin inhibited the growth and development of larvae, comparing to individual NPV-infected larvae. Notably, we observed a significant enrichment of differentially expressed genes involved in the cytochrome P450-mediated metabolism pathway between the NPV-infected and allicin combined with NPV-treated groups. The silencing of CYP340AA1 through RNA interference significantly increased the mortality of larvae infected with SeMNPV. This investigation indicates that allicin might be a potential candidate for improving the performance of the NPV against insect herbivores and identifies that CYP340AA1 gene is important in this process.