文献类型：期刊文献

英文题名：2D Photonic Crystal Hydrogel Sensor for Tear Glucose Monitoring

作者：Chen, Cheng[1,2];Dong, Zin-Giang[1];Shen, Jian-Hua[3];Chen, Hao-Wen[1];Zhu, Yi-Hua[3];Zhu, Zhi-Gang[1,2]

机构：[1]Shanghai Polytech Univ, Sch Environm & Mat Engn, Coll Engn, 2360 Jinhai Rd, Shanghai 201209, Peoples R China;[2]Shanghai Innovat Inst Mat, Shanghai 200444, Peoples R China;[3]East China Univ Sci & Technol, Sch Mat Sci & Engn, Minist Educ, Key Lab Ultrafine Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2018

卷号：3

期号：3

起止页码：3211

外文期刊名：ACS OMEGA

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000427939400082)】；

基金：This work was supported by the National Natural Science Foundation of China (61471233, 21504051), the Program for Professor of Special Appointment (Eastern Scholar) at SIHL, the Sailing Project and Basic Research Program from Science and Technology Commission of Shanghai Municipality (14YF1410600), and the key subject of Shanghai Polytechnic University (Material Science and Engineering, XXKZD1601).

语种：英文

摘要：Photonic crystal (PC) materials have huge potentials as sensors for noninvasive and real-time monitoring glucose in tears. We developed a glucose-sensitive PC material based on monolayered colloidal crystals (MCCs). Polystyrene nanoparticles were first self-assembled into a highly ordered MCC, and this two-dimensional (2D) template was then coated by a 4-boronobenzaldehyde-functionalized poly(vinyl alcohol) hydrogel. Such a sensor efficiently diffracts visible light, whose structural color could change from red through yellow to green, as the glucose concentration altered from 0 to 20 mM, covering both tears' and bloods' physiological ranges. The sensor also represents a rapid response within 180 s at each titration of glucose, combining the characteristics of high accuracy and sensitivity in detecting the glucose concentration in tears, and this intelligent sensing material presents certain possibility for the frontier point-of-care glucose monitoring.