文献类型：期刊文献

英文题名：Non-antibiotics matter: Evidence from a one-year investigation of livestock wastewater from six farms in East China

作者：Wu, Dongquan[1,2];Sui, Qian[2,3];Mei, Xuebing[2];Yu, Xia[2];Gu, Yuan[1,2];Zhao, Wentao[1,3]

机构：[1]Tongji Univ, Coll Environm Sci & Engn, State Key Lab Pollut Control & Resource Reuse, Shanghai 200092, Peoples R China;[2]East China Univ Sci & Technol, Sch Resources & Environm Engn, State Environm Protect Key Lab Environm Risk Asses, Shanghai 200237, Peoples R China;[3]Shanghai Inst Pollut Control & Ecol Secur, Shanghai 200092, Peoples R China

年份：2022

卷号：846

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：;EI(收录号：20223012410309);WOS:【SCI-EXPANDED(收录号:WOS:000831579800006)】；

基金：This research was partly supported by the National Natural Science Foundation of China (21777042, 21577033, and 22076045) , Shanghai Talent Development Funding, and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：Pharmaceutical; Non-antibiotic; Livestock wastewater; Priority; indicator

摘要：Livestock wastewater is an important source of pharmaceuticals in aquatic environments; however, most related studies only focused on antibiotics. This study investigated 18 pharmaceutical active compounds (PhACs), including 12 antibiotics and 6 non-antibiotics, in livestock wastewater during a one-year survey of six livestock farms in East China. The results showed that four non-antibiotic PhACs-caffeine, N,N-diethyl-m-toluamide, gemfibrozil, and diclofenac- exhibited high detection frequencies (80% to 97%), high concentrations (median 0.43 to 3.79 mu g/L), poor removal efficiencies (3% to 53%), and high environmental risks. A ranking system was developed to prioritize PhACs based on their occurrence, removal, and environmental risks in livestock wastewater; diclofenac, N,N-diethyl-m-toluamide, sulfamethazine, sulfadiazine, and gemfibrozil, were identified as the top five priority PhACs that should be considered first. Finally, a preliminary source apportionment protocol using four priority PhACs was proposed to trace the emission originating from treated and untreated livestock wastewater and to indicate the major contributor (cattle or swine farms) in the region. To the best of our knowledge, this is the first long-term investigation on the pollution characteristics of non-antibiotics in livestock wastewater in China, and our findings highlight the importance of considering nonantibiotics and the prioritized PhACs for the pollution control of PhACs in livestock wastewater.