文献类型：会议论文

英文题名：Enhancing the efficacy of photodynamic therapy (PDT) via water-soluble pillar[5]arene-based supramolecular complexes

作者：Wu, Jian;Tian, Jia;Rui, Leilei;Zhang, Weian[1]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Key Lab Specially Funct Polymer Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Related Technol Minist Educ, 130 Meilong Rd, Shanghai 200237, Peoples R China

会议论文集：13th International Symposium on Macrocyclic and Supramolecular Chemistry (ISMSC)

会议日期：JUL 08-13, 2018

会议地点：Quebec City, CANADA

语种：英文

摘要：A supramolecular nanovesicle was constructed by complexation between pyrophaeophorbide A (PPhA) and water-soluble pillar[5]arene, and then a biotin-pyridinium targeting agent was introduced to its surface. This nanovesicle exhibited reduced aggregation of PPhA photosensitizers and high targeting ability towards cancer cells, thereby leading to excellent therapeutic efficacy under red light.