文献类型：期刊文献

英文题名：Preparation of poly(vinylpyrrolidone)-protected Prussian blue nanoparticles-modified electrode and its electrocatalytic reduction for hemoglobin

作者：Xian, Yuezhong[1,2]; Zhou, Yuyan[1]; Xian, Yang[1]; Zhou, Lihui[3]; Wang, Haiting[1]; Jin, Litong[1]

机构：[1]E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China;[2]Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China;[3]E China Univ Sci & Technol, Ctr Anal & Res, Shanghai 2000237, Peoples R China

年份：2005

卷号：546

期号：2

起止页码：139

外文期刊名：ANALYTICA CHIMICA ACTA

收录：;EI(收录号：2005299229218);WOS:【SCI-EXPANDED(收录号:WOS:000230684100002)】；

语种：英文

外文关键词：prussian blue (PB) nanoparticles; poly(vinylpyrrolidone) (PVP); electrochemical catalysis; hemoglobin (Hb)

摘要：In this paper, a novel modified electrode was developed by using highly dispersed Prussian blue (PB) nanoparticles protected by poly(vinylpyrrolidone) (PVP). The size of the nanoparticles was controlled through adjusting the feed ratio of PVP/Fe2+. Physical characteristics of the nanocomposite were studied by transmission electron microscopy (TEM), UV-vis, IR spectroscopy, and X-ray powder diffraction (XRPD) analysis. The electrocatalytic reduction of hemoglobin (Hb) at PVP-protected PB nanoparticles (PVP/PB NPs)-modified electrode had been investigated. In addition, the size effects and biocompatibility of PVP/PB NPs for the electrochemistry of Hb were also observed. Experimental results indicated that the reduction peak currents of Hb were linear with its concentrations over the range from 1.0 x 10(-7) to 1.2 x 10(-5) mol/L and the calculated detection limit (S/N = 3) was 4.0 x 10(-8) mol/L. (c) 2005 Elsevier B.V. All rights reserved.