文献类型：期刊文献

英文题名：A High-Linearity Glucose Sensor Based on Silver-Doped Con A Hydrogel and Laser Direct Writing

作者：Hu, Yulin[1,2];Yang, Dasheng[1,2];Zhang, Hongbo[1];Gao, Yang[1,2];Zhang, Wenjun[3];Yin, Ruixue[1,2]

机构：[1]East China Univ Sci & Technol, Sch Mech & Power Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Shanghai Key Lab Intelligent Sensing & Detect Tech, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Univ Saskatchewan, Div Biomed Engn, 57 Campus Dr, Saskatoon, SK S7N 5A9, Canada

年份：2023

卷号：15

期号：6

外文期刊名：POLYMERS

收录：;EI(收录号：20231613936978);WOS:【SCI-EXPANDED(收录号:WOS:000959744100001)】；

基金：This research was funded by Shanghai Science and Technology Innovation Program (No. 19441909600), the Opening project of Shanghai Key Laboratory of Orthopedic Implant (KFKT2019001), and the National Natural Science Foundation of China (Grant No. 52275146, 21404038).

语种：英文

外文关键词：laser direct writing; enzyme-free glucose sensor; silver particles; glucose-responsive; hydrogels

摘要：A continuous glucose monitoring (CGM) system is an ideal monitoring system for the blood glucose control of diabetic patients. The development of flexible glucose sensors with good glucose-responsive ability and high linearity within a large detection range is still challenging in the field of continuous glucose detection. A silver-doped Concanavalin A (Con A)-based hydrogel sensor is proposed to address the above issues. The proposed flexible enzyme-free glucose sensor was prepared by combining Con-A-based glucose-responsive hydrogels with green-synthetic silver particles on laser direct-writing graphene electrodes. The experimental results showed that in a glucose concentration range of 0-30 mM, the proposed sensor is capable of measuring the glucose level in a repeatable and reversible manner, showing a sensitivity of 150.12 omega/mM with high linearity of R-2 = 0.97. Due to its high performance and simple manufacturing process, the proposed glucose sensor is excellent among existing enzyme-free glucose sensors. It has good potential in the development of CGM devices.