文献类型：期刊文献

英文题名：Chitin oligosaccharides for the food industry: production and applications

作者：Zhang, Ran[1,2];Zhao, Qiong[1,2];Yi, Zhenwei[1,2];Zhang, Kaihang[1,2];Shi, Jinqi[1,2];Zhu, Liangliang[1,2];Chen, Yijia[1,2];Jin, Jiayang[1,2];Zhao, Liming[1,2,3]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]Shanghai Collaborat Innovat Ctr Biomfg Technol SCI, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met, Sch Pharm, 130 Mei Long Rd, Shanghai 200237, Peoples R China

年份：2023

卷号：3

期号：1

起止页码：49

外文期刊名：SYSTEMS MICROBIOLOGY AND BIOMANUFACTURING

收录：EI(收录号：20233414609150);WOS:【ESCI(收录号:WOS:001205748000011)】；

基金：This work was supported by the National Key R & D Program of China (2019YFD0901805), the 111 Project (B18022), the Fundamental Research Funds for the Central Universities, the Open Project Funding of the State Key Laboratory of Bioreactor Engineering, ECUST (ZDXM2019), and Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism (Shanghai Municipal Education Commission).

语种：英文

外文关键词：Chitin; Chitin oligosaccharides; Chitooligosaccharides; Production; Food applications

摘要：Chitin oligosaccharides (CHOS), high-value-added oligomers linked by N-acetyl-d-glucosamine (GlcNAc, NAG), and a small amount of d-glucosamine (GlcN, GA), have aroused increasing interest due to their excellent biological properties, including antibacterial, anti-inflammatory, and immunoprotective activities, and intestinal regulation. The efficient production and utilization of CHOS with high performance can solve problems from chitin as biowaste. However, the large-scale production of well-defined CHOS has not been fully accomplished due to the limited biotechnology and separation methods, thus impeding the research on their biological functions as well as their accurate applications. In this review, we comprehensively summarize the current preparation methods of CHOS, including the chemical, physical, enzymatic and biosynthetic methods. The advantages and disadvantages of the methods are discussed in terms of efficiency, economy, and environmental effects. Furthermore, the applications of CHOS in the food industry and their contributions to human health based on their excellent bioactivities are expounded. It is hoped that this review will help in providing new insights into the production of CHOS with high precision, and support the application of CHOS in serving the food industry as nutritional supplements or foods for special medical purposes.