文献类型：期刊文献

英文题名：Overcoming challenges in the analysis of short-chain per- and polyfluoroalkyl substances in raw landfill leachates: Clean-up method optimization and interference identification

作者：Chen, Liping[1];Wang, Jiaxi[1];Yu, Xia[1];Cai, Lankun[1];He, Kai[2];Yuan, Jinlong[2];Sui, Qian[1,3]

机构：[1]East China Univ Sci & Technol, Sch Resources & Environm Engn, State Environm Protect Key Lab Environm Risk Asses, Shanghai 200237, Peoples R China;[2]Sun Yat Sen Univ, Sch Civil Engn, Zhuhai 519082, Peoples R China;[3]Shanghai Inst Pollut Control & Ecol Secur, Shanghai 200092, Peoples R China

年份：2025

卷号：489

外文期刊名：JOURNAL OF HAZARDOUS MATERIALS

收录：;EI(收录号：20250717859010);WOS:【SCI-EXPANDED(收录号:WOS:001427392700001)】；

基金：This research was partly supported by the National Key R & D Pro-gram of China (2023YFC3711600) , the National Natural Science Foundation of China (22376066) , the Postdoctoral Innovation Talents Support Program (BX20230123) , the China Postdoctoral Science Foun-dation (2023M741171) , the Science and Technology Commission of Shanghai Municipality's Yangfan Special Project (23YF1408400) , and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：Per; and polyfluoroalkyl substances (PFASs); Clean-up method; Interference identification; Graphitized carbon black (GCB); Raw landfill leachate

摘要：Municipal solid waste (MSW) landfill leachate is an important emission hotspot for per- and polyfluoroalkyl substances (PFASs) in the water environment. However, quantifying short-chain PFASs in raw landfill leachate is challenging due to severe matrix effects that occur during liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. To overcome this obstacle, an enhanced clean-up method was developed for the accurate determination of short-chain PFASs in raw landfill leachate. This method involved comparing various graphitized carbon black (GCB) adsorbents and purification sequences. The results showed that the GCB cartridge exhibited optimal purification efficiency when applied directly to raw leachate samples. It achieved recoveries for all 6 short-chain PFASs ranging from 85 % to 113 %, with RSDs <= 7.2 %. In particular, perfluorobutanoic acid (PFBA) and perfluoropentanoic acid (PFPeA) were most effectively separated from interfering co-extracts during chromatographic analysis, as compared to other purification strategies. Humic acid-like substances were characterized as the main components causing interference. By applying the modified method, the total concentrations of the 6 short-chain PFAS targets were found to range from 10.7 to 22.7 mu g/L, representing 33.0-93.7 % of total PFASs detected. This study presents an effective approach to the extraction of short-chain PFASs from complex environmental matrices, which is important for the comprehensive determination of PFAS profiles in raw landfill leachate.