文献类型：期刊文献

中文题名：解草酯的合成及动力学

英文题名：Synthesis of Cloquintocet-mexyl and Its Reaction Kinetics

作者：张玥[1];彭阳峰[1]

机构：[1]华东理工大学化工学院,上海200237

年份：2015

卷号：32

期号：4

起止页码：416

中文期刊名：应用化学

外文期刊名：Chinese Journal of Applied Chemistry

收录：CSTPCD;;北大核心:【北大核心2014】；CSCD:【CSCD2015_2016】；

语种：中文

中文关键词：解草酯;氯羟基喹啉;氯乙酸甲基己基酯;反应动力学

外文关键词：cloquintocet-mexyl; chloro-hydroxyquinoline ; methylhexyl chloroacetate; reaction kinetic

摘要：针对原有生产上存在过程繁琐,收率不高等缺点,以5-氯-8羟基喹啉和氯乙酸-1-甲基己基酯为起始原料,研究了解草酯的合成工艺条件,确定了反应所用的碱、反应时间以及加入的5-氯-8-羟基喹啉与氯乙酸-1-甲基己基酯和碳酸钾与氯乙酸-1-甲基己基酯的摩尔比。在解草酯合成工艺条件的基础上,进一步探讨了解草酯合成的反应动力学,确定该反应符合二级反应条件,得到了323、328、333和339 K不同温度下的反应动力学方程式-r2=-dc2dt=1.46×108e(-49.82×103/RT)c1c2,依据所得的不同温度下的反应速率常数,计算了该反应的活化能与频率因子,所得的反应的活化能和频率因子分别为49.82 k J/mol和1.46×108,为合成解草酯的工业放大提供了理论指导。
In order to increase the yield and optimize the process of preparation for cloquintocet-mexyl in industrial, the synthesis of cloquintocet-mexyl in this paper was investigated using 5-chloro-8-hydroxyquinoline and methylhexyl chloroacetate as raw materials. The alkali used in the reaction, reaction time, the molar ratio of 5-chloro-8-hydroxyquinoline to methylhexyl chloroacetate and the molar ratio of potassium carbonate to methylhexyl chloroacetate were determinated. The kinetic equation for this reaction was established. The result shows that the synthesis of cloquintocet-mexyl is a second-order reaction. The kinetics experiments were carried out at 323 K, 328 K, 333 K, 339 K, respectively. The frequency factor is 49. 82 kJ/mol and the activation energy is 49.82 kJ/mol which are obtained from the reaction rate constants at different temperatures by using the Arrhenius equation. The reaction kinetic equation is -r2=-^dc2/dt=1.46×10^8e^（-49.82×10^3/RT）c1c2,It provides the basic data for the industrial development of cloquintocet-mexyl.