文献类型：期刊文献

英文题名：Development of a Telescoped Process for Preparation of N,O-Chelated Diarylborinates

作者：Guan, Changwei[1];Huang, Lingyun[1];Ren, Chao[1];Zou, Gang[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Dept Fine Chem, 130 Meilong Rd, Shanghai, Peoples R China

年份：2018

卷号：22

期号：7

起止页码：824

外文期刊名：ORGANIC PROCESS RESEARCH & DEVELOPMENT

收录：;EI(收录号：20182705399767);WOS:【SCI-EXPANDED(收录号:WOS:000439761300009)，CCR-EXPANDED(收录号:WOS:000439761300009)】；

基金：We thank the National Natural Science Foundation of China (21472041) and National Key Technology R&D Program, the Ministry of Science and Technology of China (2015BAK44B00) for financial support.

语种：英文

外文关键词：chelated diarylborinate; one-pot reaction; Barbier-type condition; telescoped process

摘要：A telescoped process has been developed for practical preparation of N,O-chelated four-coordinate diarylborinates via direct reaction of N,O-chelate ligands with a diarylborinate solution prepared by removal of magnesium via precipitation from a one-pot reaction of aryl bromides, magnesium, and tributylborate. Ten N,O-chelated diarylborinates of representative N,O-chelate ligands of 2-picolinic acid, quinolin-8-ol, N-dimethylglycine, and amino alcohols were readily obtained in good yields. The telescoped process not only minimizes chemical waste and circumvents tedious purification of diarylborinic acids but also eliminates handling of Grignard reagents and improves compatibility with acid-sensitive groups.