文献类型：期刊文献

英文题名：Controllable and facile synthesis of poly(2-oxazoline)s using trimethylsilyl trifluoromethanesulfonate as the initiator

作者：Zhou, Min[1];Ji, Zhemin[2];Xiao, Ximian[2];Liu, Longqiang[2];Cui, Ruxin[2];Luo, Zhengjie[2];Cong, Zihao[2];Liu, Runhui[1,2,3]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Mat Sci & Engn, Key Lab Ultrafine Mat, Minist Educ, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Shenzhen Res Inst, Shenzhen, Peoples R China

年份：2023

卷号：14

期号：9

起止页码：1064

外文期刊名：POLYMER CHEMISTRY

收录：;EI(收录号：20230913647345);WOS:【SCI-EXPANDED(收录号:WOS:000928753000001)】；

基金：This research was supported by the National Natural Science Foundation of China (no. 22075078 and 21861162010), Free Exploring Basic Research Project at Shenzhen Research Institute of ECUST (2021Szvup042), Program of Shanghai Academic/Technology Research Leader (20XD1421400), China National Postdoctoral Program for Innovative Talents (BX2021102), and China Postdoctoral Science Foundation (2022M710050).

语种：英文

外文关键词：Biocompatibility - Block copolymers

摘要：Poly(2-oxazoline)s have received more and more attention in biomedical fields for their hydrophilicity and excellent biocompatibility. Poly(2-oxazoline)s can act as functional peptide mimics and promising substitutes for polyethylene glycol. Therefore, it is of great importance to develop new polymerization methods for the synthesis of functional poly(2-oxazoline)s with diverse structures. Herein, we report a controllable and facile synthesis of poly(2-oxazoline)s using trimethylsilyl trifluoromethanesulfonate (TMSOTf) as the initiator. This polymerization presents temperature-dependent characteristics, showing a decrease in polymerization time from a week to hours by increasing the reaction temperature. Based on TMSOTf-initiated polymerization, poly(2-oxazoline)s were obtained in a controllable way with expected chain length, variable side chain functional groups and narrow dispersities. This living polymerization on 2-oxazolines also enables facile synthesis of statistical and block copolymers of poly(2-oxazoline) and will contribute to the functional study and application of poly(2-oxazoline).