文献类型：期刊文献

英文题名：An efficient silica-grafted poly-(L)-leucine catalyst for asymmetric epoxidation of α,β-unsaturated ketone

作者：Yang, Fan[1]; He, Lin-Mei[1]; Yi, Hua[1]; Zou, Gang[2]; Tang, Jie[1]; He, Ming-Yuan[3]

机构：[1]E China Normal Univ, Inst Med Chem, Dept Chem, Shanghai 200062, Peoples R China;[2]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]E China Normal Univ, Dept Chem, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China

年份：2007

卷号：273

期号：1-2

起止页码：1

外文期刊名：JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL

收录：;EI(收录号：20072710688142);WOS:【SCI-EXPANDED(收录号:WOS:000248178000001)】；

语种：英文

外文关键词：silica-grafted poly-(L)-leucine catalyst; asymmetric epoxidation; alpha,beta-unsaturated ketone

摘要：A new efficient covalent immobilization method for preparation of silica-grafted poly-(L)-leucine catalyst AP-PLL-Silica gel was developed. The AP-PLL-Silica gel catalyzed asymmetric epoxidation of benzalacetophenone, yielding optically active epoxy ketone in high enantioselectivity up to 97% e.e. The catalyst was easily separated and reused several times with DO significant loss of activity and enantio selectivity. (C) 2007 Elsevier B.V. All rights reserved.