文献类型：期刊文献

英文题名：Surface modification of silicon wafer by grafting zwitterionic polymers to improve its antifouling property

作者：Sun, Yunlong[1];Chen, Changlin[1];Xu, Heng[3];Lei, Kun[1];Xu, Guanzhe[1];Zhao, Li[2];Lang, Meidong[1]

机构：[1]East China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai Key Lab Adv Polymer Mat, Key Lab Ultrafine Mat,Minist Educ, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, New World Inst Biotechnol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[3]Collaborat Innovat Ctr Petrochem New Mat, Anqing 246011, Anhui, Peoples R China

年份：2017

卷号：419

起止页码：642

外文期刊名：APPLIED SURFACE SCIENCE

收录：;EI(收录号：20172203702030);WOS:【SCI-EXPANDED(收录号:WOS:000404816900075)】；

基金：This research was supported by National Key Technology Support Program (2015BAD16B05-04) and Natural Science Foundation of Shanghai (No.2013ZR1412100).

语种：英文

外文关键词：Silicon wafer; Zwitterionic polymer; Antifouling ability; 4-vinyl pyridine; Bacterium; Bovine serum albumin

摘要：Silicon (111) wafer was modified by triethoxyvinylsilane containing double bond as an intermedium, and then P4VP (polymer 4-vinyl pyridine) brush was "grafted" onto the surface of silicon wafer containing reactive double bonds by adopting the "grafting from" way and Si-P4VP substrate (silicon wafer grafted by P4VP) was obtained. Finally, P4VP brush of Si-P4VP substrate was modified by 1,3-propanesulfonate fully to obtain P4VP-psl brush (zwitterionic polypyridinium salt) and the functional Si-P4VP-psl substrate (silicon wafer grafted by zwitterionic polypyridinium salt based on polymer 4-vinyl pyridine) was obtained successfully. The antifouling property of the silicon wafer, the Si-P4VP substrate and the Si-P4VP-psl substrate was investigated by using bovine serum albumin, mononuclear macrophages (RAW 264.7) and Escherichia coli (E. coli)AITC25922 as model bacterium. The results showed that compared with the blank sample-silicon wafer, the Si-P4VP-psl substrate had excellent anti-adhesion ability against bovine serum albumin, cells and bacterium, due to zwitterionic P4VP-psl brush (polymer 4-vinyl pyridine salt) having special functionality like antifouling ability on biomaterial field. (C) 2017 Elsevier B.V. All rights reserved.