文献类型：期刊文献

英文题名：Organocatalytic Aerobic Oxidation of Benzylic sp3 C-H Bonds of Ethers and Alkylarenes Promoted by a Recyclable TEMPO Catalyst

作者：Zhang, Zhiguang[1,2];Gao, Yuan[1,2];Liu, Yuan[1,2];Li, Jianjun[1,2];Xie, Hexin[1,2];Li, Hao[1,2];Wang, Wei[1,2,3]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, State Key Lab Bioengn Reactor, Shanghai 200237, Peoples R China;[3]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

年份：2015

卷号：17

期号：21

起止页码：5492

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000364434900087)，CCR-EXPANDED(收录号:WOS:000364434900087)】；

基金：Financial support of this research from the program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning (No. 201226, H. L.), the National Science Foundation of China (21372073, 21572054 and 21572055), the Fundamental Research Funds for the Central Universities and East China University of Science and Technology, and the China 111 Project (Grant B07023) is gratefully acknowledged.

语种：英文

摘要：An entirely metal-free catalyst system consisting of an easily prepared recyclable new TEMPO derived sulfonic salt catalyst, and mineral acids (NaNO2 and HCl) has been developed for selective aerobic oxidation of structurally diverse benzylic sp(3) C-H bonds of ethers and alkylarenes. The mild reaction conditions allow for the generation of synthetically and biologically valued isochromanones and xanthones from readily accessible alkyl aromatic precursors in good yields.