文献类型：期刊文献

英文题名：Rapid fabrication of physically robust hydrogels

作者：Bao, Bingkun[1];Zeng, Qingmei[1];Li, Kai[2,3,4];Wen, Jianfeng[5];Zhang, Yiqing[2,3,4];Zheng, Yongjun[3,4];Zhou, Renjie[2,3,4];Shi, Chutong[1];Chen, Ting[1];Xiao, Chaonan[1];Chen, Baihang[2,3,4];Wang, Tao[5];Yu, Kang[6];Sun, Yuan[6];Lin, Qiuning[1];He, Yong[6];Tu, Shantung[5];Zhu, Linyong[1,2,3,4]

机构：[1]Shanghai Jiao Tong Univ, Sch Biomed Engn, Shanghai, Peoples R China;[2]East China Univ Sci & Technol, Optogenet & Synthet Biol Interdisciplinary Res Ctr, Shanghai Collaborat Innovat Ctr Biomfg Technol, State Key Lab Bioreactor Engn, Shanghai, Peoples R China;[3]East China Univ Sci & Technol, Key Lab Adv Mat, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn, Shanghai, Peoples R China;[4]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn, Joint Int Res Lab Precis Chem & Mol Engn, Shanghai, Peoples R China;[5]East China Univ Sci & Technol, Sch Mech & Power Engn, Key Lab Pressure Syst & Safety, Minist Educ, Shanghai, Peoples R China;[6]Zhejiang Univ, Coll Mech Engn, State Key Lab Fluid Power & Mechatron Syst, Hangzhou, Peoples R China

年份：2023

卷号：22

期号：10

起止页码：1253

外文期刊名：NATURE MATERIALS

收录：;EI(收录号：20233414606014);WOS:【SCI-EXPANDED(收录号:WOS:001052548100001)】；

基金：We thank Q. Shan, H. Li and X. Guo at Shanghai Jiao Tong University for technical assistance and F. Wang and P. Sun at Nankai University for the NMR characterization of gels. This work was financially supported by the National Key Research and Development Program of China (2019YFA0110500, L.Z. and Q.L.; 2021YFC2701400, Q.L.; 2019YFA0904800, L.Z.), the National Natural Science Foundation of China (22022506, Q.L.; 32121005, L.Z.; 21937004, L.Z.) and the Interdisciplinary Program of Shanghai Jiao Tong University (YG2022ZD017, Q.L.; YG2022ZD009, L.Z.), as well as the Young Leading Scientists Cultivation Plan supported by the Shanghai Municipal Education Commission (ZXWH1082101, Q.L.).

语种：英文

外文关键词：3D printing - Biocompatibility - Biomimetics - Elastomers - Fabrication - Gels - Nanocomposites - Stability - Tensile strength

摘要：Hydrogels are promising materials but are often limited by inadequate mechanical properties and time-consuming fabrication processes. Here the authors demonstrate a rapid biomimetic interfacial-bonding nanocomposite strategy for ultra-tough hydrogels with high tensile strength. Hydrogel materials show promise for diverse applications, particular as biocompatible materials due to their high water content. Despite advances in hydrogel technology in recent years, their application is often severely limited by inadequate mechanical properties and time-consuming fabrication processes. Here we report a rapid hydrogel preparation strategy that achieves the simultaneous photo-crosslinking and establishment of biomimetic soft-hard material interface microstructures. These biomimetic interfacial-bonding nanocomposite hydrogels are prepared within seconds and feature clearly separated phases but have a strongly bonded interface. Due to effective interphase load transfer, biomimetic interfacial-bonding nanocomposite gels achieve an ultrahigh toughness (138 MJ m(-3)) and exceptional tensile strength (15.31 MPa) while maintaining a structural stability that rivals or surpasses that of commonly used elastomer (non-hydrated) materials. Biomimetic interfacial-bonding nanocomposite gels can be fabricated into arbitrarily complex structures via three-dimensional printing with micrometre-level precision. Overall, this work presents a generalizable preparation strategy for hydrogel materials and acrylic elastomers that will foster potential advances in soft materials.