文献类型：期刊文献

英文题名：A Surface Enhanced Raman Scattering (SERS) microdroplet detector for trace levels of crystal violet

作者：Liu, Bingxiang[1,2];Jiang, Wei[3];Wang, Haiting[3];Yang, Xiaohui[1,2];Zhang, Sanjun[4];Yuan, Yufeng[4];Wu, Ting[1,2];Du, Yiping[1,2]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Res Ctr Anal & Test, Shanghai 200237, Peoples R China;[3]Shanghai Entry Exit Inspect & Inspect & Quarantin, Tech Ctr Ind Prod & Raw Mat Inspect & Testing, Shanghai 200135, Peoples R China;[4]E China Normal Univ, State Key Lab Precis Spect, Shanghai 200062, Peoples R China

年份：2013

卷号：180

期号：11-12

起止页码：997

外文期刊名：MICROCHIMICA ACTA

收录：;EI(收录号：20242616514208);WOS:【SCI-EXPANDED(收录号:WOS:000322524100006)】；

基金：This work was supported by National Science Foundation of China (grant No: 21205041, No: 61008003), a grant from Research Center of Analysis and Test of East China University of Science and Technology, China, and Shanghai Rising-Star Program (No: 11QA1402100).

语种：英文

外文关键词：Micro total analysis system; Microdroplet; Surface-enhanced Raman scattering (SERS); Crystal violet (CV)

摘要：We report on a microfluidic platform that integrates a winding microdroplet chip and a surface-enhanced Raman scattering (SERS) detection system for trace determination of crystal violet (CV). Colloidal silver was applied to generate SERS. Compared to the continuous flow microfluidic system, the microdroplet based detection described here effectively eliminates any memory effects. Effects of flow pattern, droplet size, surfactant, and position of detection were optimized. Under optimal conditions, there is a linear correlation between signal and the concentration of CV in the 10 nM to 800 nM range, with a correlation coefficient (R-2) of 0.9967. The limit of detection in water is 3.6 nM.