文献类型：期刊文献

英文题名：Highly stereoselective synthesis of aryl/heteroaryl-C-nucleosides via the merger of photoredox and nickel catalysis

作者：Yingying[1,2];Liu, Shihui[3];Xi, Yifan[1,2];Li, Hongrui[1,2];Yang, Kai[1,2];Cheng, Zhihao[1,2];Wang, Wei[1,2,4,5];Zhang, Yongqiang[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioengn Reactor, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Jiaxing Univ, Coll Med, 56 South Yuexiu Rd, Jiaxing 314033, Peoples R China;[4]Univ Arizona, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA;[5]Univ Arizona, Inst BIO5, Tucson, AZ 85721 USA

年份：2019

卷号：55

期号：97

起止页码：14657

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000501150200021)】；

基金：Financial support from the program of the National Natural Science Foundation of China (21602060, 21871086, Y.-Q. Z.; 21572055, 21738002, W. W.) and the Chinese Fundamental Research Funds for the Central Universities (ECUST: WY1714033) is gratefully acknowledged.

语种：英文

摘要：A photoredox/nickel dual-catalyzed decarboxylative cross-coupling reaction of anomeric ribosyl/deoxyribosyl acids with aryl/heteroaryl bromides has been developed. The reaction proceeds smoothly under visible-light irradiation and features the using of cost-effective and easily handled catalysts and starting materials, which allows the highly stereoselective synthesis of diverse aryl/heteroaryl-C-nucleosides in moderate to high yields.