文献类型：会议论文

英文题名：Whole-Cell Biocatalytic Processes with Ionic Liquids

作者：Xu, Pei[1,3];Zheng, Gao-Wei[2];Du, Peng-Xuan[3];Zong, Min-Hua[3];Lou, Wen-Yong[1,3]

机构：[1]S China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Guangdong, Peoples R China;[2]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[3]S China Univ Technol, Sch Light Ind & Food Sci, Lab Appl Biocatalysis, Guangzhou 510640, Guangdong, Peoples R China

会议论文集：6th International Congress on Ionic Liquids (COIL-6)

会议日期：JUN 16-20, 2015

会议地点：Jeju City, SOUTH KOREA

语种：英文

外文关键词：Whole-cell; Ionic liquid; Biocatalysis; Biocompatibility; Biodegradability

摘要：Whole-cell-based biocatalysis in ionic liquids (ILs)-containing systems has attracted increasing interest in recent years. Compared to bioreactions catalyzed by isolated enzymes, the major advantages of using whole cell in biocatalytic processes are that cells provide a natural intracellular environment for the enzymes to function with cofactors regeneration in situ. An increasing number of renewable ILs are now accessible as a result of the ongoing progress in designing strategy of ILs and the sustainable environment requirement. The toxicity of ILs to microbial cells and the biodegradability are two of the crucial factors that allow the biocatalysis in Its being applied in practice rather than in bench-scale. Applications of whole-cell biocatalysis in IL-containing systems have, to date, been focused on the production of valuable compounds, mainly through reduction, oxidation, and hydrolytic reactions. The mechanism research of ILs affecting the whole-cell biocatalysis offers the possibility to integrate effectively ILs with biotransformation. Thus, a comprehensive understanding of the whole-cell-based biocatalytic process with ILs will contribute to the discovery of novel solvent for enzymatic reaction and the synthesis of more valuable compounds.