文献类型：期刊文献

中文题名：聚乳酸固相缩聚模型

英文题名：Modeling of solid-state polymerization of PLLA

作者：钱刚[1];王海娟[1];周兴贵[1];袁渭康[1]

机构：[1]华东理工大学联合化学反应工程研究所,上海200237

年份：2005

卷号：56

期号：1

起止页码：157

中文期刊名：化工学报

外文期刊名：CIESC Journal

收录：CSTPCD;;EI(收录号：2005129008107);Scopus;北大核心:【北大核心2004】；CSCD:【CSCD2011_2012】；

基金：教育部全国优秀博士论文专项基金 ;上海市科委"曙光"计划资助项目~~

语种：中文

中文关键词：聚乳酸;固相缩聚;模型;活化能

外文关键词：Activation energy;Chemical reactions;Degradation;Numerical methods;Polycondensation;Reaction kinetics

摘要：提出了聚乳酸固相缩聚的反应 扩散综合模型 ,该模型中考虑了可逆酯化反应和热降解反应 .并由实验数据拟合得到了不同温度下各反应的速率常数以及水的扩散系数 ,进而得到它们的活化能 ;模拟了不同因素对固相缩聚过程的影响 .研究表明在较低的温度下 ,热降解反应的影响较小 ,可以忽略 ;而在较高温度下 ,其影响显著 .水的扩散速率对聚乳酸分子量的增长影响很大 ;小粒径颗粒有利于制备高分子量聚乳酸 .
A reaction and diffusion model is developed for the process of solid-state polymerization (SSP) to increase the molecular mass of poly (L-lactic acid) (PLLA). Three reactions are considered: forward and backward polycondensation reactions and thermal degradation reaction. The rate constants of these reactions and diffusivity of water are obtained by fitting the model to experimental data, on the basis of which the activation energies were estimated. Degradation is found to be insignificant at low reaction temperature, while at high reaction temperature it becomes important and cannot be neglected. The diffusivity of water has an important effect on molecular mass growth. Small particle is favorable to obtain a high molecular mass product.